Genome Analysis & Transcriptomics (2KV)

Course no.: 365.081
Lecturer: Alois Regl (alois.regl@regl.net, +43 664 4502030)
Pre-meeting: tba
Times/locations: Tue 8:30-11:00, room S3 057
Fri 8:30-11:00, room S3 048 (exception: Fri March 17 = room S3 058!)
The final schedule for both lectures (Structural Bioinformatics/Genome Analysis & Transcriptomics) will be presented on tba.
Start: Tue March 7, 2017
Mode: KV, 2h, weekly
Registration: KUSSS

Lecture notes:

There are no lecture notes but all slides will be provided via KUSSS.

Motivation and course outline

Bioinformatics is an interdisciplinary field at the interface of life sciences and computational sciences that deals with the development and application of methods for storing, retrieving, and, in particular, analyzing biological data. The massive data amounts produced by recent and currently emerging high-throughput biotechnologies provide unprecedented potentials, but also pose yet unseen computational challenges making bioinformatics an essential success factor for the advancement of fields, such as, molecular biology, genetics, medicine, and pharmacology.

The goal of this course is to provide an overview of foundational and computational aspects of genetic variation and gene expression. The first part is mainly concerned with genetic commonalities and differences between individuals, how these commonalities and differences emerge, and how they can be associated to diseases and other traits. The second part is concerned with the dynamics of genes, how they are organized, how they can be detected, how the activation of genes is controlled, and how gene expression can be measured and analyzed computationally.

Genome Analysis: Transcriptomics:

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